Modern trends in tear replacement therapy for patients with dry eye syndrome

Today, the dry eye syndrome therapy is based on techniques aimed at compensating for loss of moisture in conjunctival cavity (the so-called tear replacement therapy) either by additional moistening surface, or maintaining cavity. Traditionally, first step to moisturise and artificial products leader this area. In recent years, natural mucopolysaccharides are one basic components tears that attract greatest practical interest, among them hyaluronic acid, rather its sodium salt, which almost identical pharmacological properties native acid with respective molecular weight. Hyaluronic characterized high mucoadhesiveness, allows solution polymer bind mucins surface prolong residence time formulation ocular surface. The even more significant property molecular-weight HyA thixotropy: has a viscosity open eye, provides good wettability preservative-free solutions thixotropy, hygroscopicity, mucoadhesiveness tolerability, priority. effectiveness such drugs been established. They provide deep hydration treatment due Sjögren's syndrome, meibomian blepharitis perimenopause, as well children. latter was developed neuroparalytic keratitis, chronic blepharitis, systematic damage drops containing preservatives.